REGENXBIO Headquarters

Rockville, MD

Montgomery County, MD, is one of the fastest-growing life sciences markets in the United States. REGENXBIO is a clinical-stage biotechnology leader advancing gene therapies through its proprietary NAV® Technology, and an integral player in that growing biopharmaceutical market. As demand grows for manufacturing space and the talent to support research and development. As REGENXBIO experienced sustained growth, it sought to consolidate operations into a single headquarters that would strengthen collaboration, streamline production, and support its expanding workforce.

 

Client REGENXBIO
Size 132,000 SF
Categories Science & Technology
Completion Date 2022
Awards

IES Section Award for Interior Lighting Design
Illuminating Engineering Society

The aesthetic is clean, sleek, and modern. White and grey finishes and materials emphasize the bold blue and orange accents.

 

A Seamless Lab-to-Office Ecosystem

This headquarters incorporates rare elements that enable the collaborative and efficient development of new potential medicines. It integrates advanced laboratories, open offices, clinical manufacturing suites, and shared amenities across five levels.

What separates this facility from cGMP manufacturing facilities? Research and BSL-2 labs occupy the third and fourth floors while the fifth floor houses the gene therapy manufacturing facility, featuring two independent bulk drug suites, 500L and 2,000L bioreactors, quality control laboratories, and a fill-finish suite. A new mechanical penthouse supports the processing cleanrooms and houses most utilities that serve the cleanroom suites.

 

High-end office space is located directly adjacent to the labs and the manufacturing area on the fifth floor of the building, bringing the entire research and development lifecycle under one roof. Each new product they develop can begin the research stages, proceed through storage and shipping, and receive final FDA approval in the same building. Throughout, large windows and floor-to-ceiling glass provide transparency between spaces, allowing natural light to enter highly controlled environments.

Open collaboration zones divide the floor plates, creating centralized hubs for spontaneous teamwork and reinforcing the company’s culture of openness and discovery.

 

Key Design Elements

  • 2,900 linear feet of lab benching for R&D, tech ops, and QC labs
  • Floor-to-ceiling digital media wall in the main lobby
  • Large open collaboration zones with exterior views on every floor
  • Demountable partitions and open ceilings for transparency and daylight
  • Brand-integrated angular geometries and accent colors
  • Distributed social hubs and flexible town hall gathering spaces
  • Full MEP/process utility design including RO/DI, WFI, vacuum, and cooling systems

“In-house manufacturing is a key differentiator for REGENXBIO as a leader in gene therapy. Quality manufacturing is crucial to all stages of AAV gene therapy development, and we’re extremely proud of this cutting-edge facility and the experienced team we have to lead these efforts. Bringing our manufacturing in-house allows us to control the process from beginning to end and provides flexibility to support a wide range of clinical and commercial needs.”

– Curran Simpson, Chief Operations and Technology Officer at REGENXBIO

 

Angular geometries that reflect the client’s logo are created thru portals, bookshelves, dividers, and ceiling planes.

 

Branding and Wellness in Every Detail

The design embodies REGENXBIO’s brand through clean lines, bold accent colors, and angular geometries inspired by the company’s logo. A digital media wall greets visitors with vision and mission statements, while subtle gradients in color and materiality help define zones of focus, connection, and calm.

 

 

Bold accents set the tone for each unique space. Deep blue in lobby and reception spaces represents trust and reliability, while orange in common areas and conference spaces references energy and connection. Softer colors in the office and wellness spaces encourage calmness and focus. White and grey finishes and materials emphasize the bold accents.

Dispersed pantries, varied seating options, and acoustically enhancing ceiling clouds support employee well-being and facilitate informal interaction. A modular layout provides flexibility for future growth.

Design the Future

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